CFSRE and Verogen Team-up to Accelerate the Implementation of Next Generation Sequencing for Law Enforcement and Practitioner Communities
WILLOW GROVE, PA / SAN DIEGO, CA, September 9, 2019—The Center for Forensic Science Research & Education (CFSRE) and Verogen have entered into a collaborative agreement to establish CFSRE as a leader in the field of forensic Next Generation Sequencing (NGS), also known as Massively Parallel DNA Sequencing (MPS).
CFSRE, supported through this collaboration, has recently completed their validation of the ForenSeq DNA Signature Prep Kit on the MiSeq FGx® platform. In the coming months, CFSRE will be working to develop training materials for law enforcement and practitioner communities, and implementing a high-quality workflow for application with casework
“We are very excited to be working with Verogen on the forefront of evaluating and implementing this new technology,” said Dr. Barry Logan, Executive Director at CFSRE. “The evaluation of new technologies that can be applied to criminal investigations is an important component of our organization’s mission.”
With this technology, a single DNA test provides a wealth of information to aid investigations along multiple vectors. The included autosomal short tandem repeat (STR) markers can be used to populate and search the CODIS U.S. National DNA Index (NDIS). The same test also provides Y-STR results for profiling male subjects, X-STR results for complicated kinship scenarios, and a large number of single nucleotide polymorphism (SNP) markers to assist with low quality samples typical in forensic contexts. Additionally, a collection of these SNPs can provide information about appearance, such as hair color, eye color, and biogeographical ancestry, to aid stalled cases with investigative leads or to rapidly refine a subject pool. This new toolbox uses best-in-class sequencing technology to add significant depth and breadth to forensic DNA analysis, while enabling recovery of results from biological evidence samples for which traditional methods have proven inadequate.
“We have been encouraged by our evaluation of this technology and its ability to recover almost twice as many genetic markers for degraded and low-level sample types as compared to traditional capillary electrophoresis-based approaches,” said Dr. Heather McKiernan, Director at CFSRE. “This technology will continue to propel genetic testing capabilities forward, helping to resolve the more challenging forensic cases encountered in this modern era.”
“We are enthusiastic to continue working with CFSRE, who have an established track record in forensic training and education, to addressthe important educational aspects of NGS adoption in forensic laboratories”,said Brett Williams, CEO of Verogen. “Their validation of the ForenSeq DNA Signature Prep Kit has shown the power and promise of this technology for contributions towards criminal justice.”
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Two CFSRE Articles Are Named “Most Downloaded” By Wiley Online Library
CFSRE is pleased to announce that two of our articles published in Drug Testing and Analysis, have been named the journal’s top downloaded recent papers!
- Analysis of fentanyl analogs and novel synthetic opioids in blood, serum/plasma, and urine in forensic casework
- Metabolism of novel opioid agonists U-47700 and U-49900 using human liver microsomes with confirmation in authentic urine specimens from drug users
According to Wiley Online Library, amongst articles published between January 2017 and December 2018, our papers are among the most downloaded in the 12 months following online publication, “generating immediate impact and visibility, contributing significantly to the advancement of the field of forensic science.”
Congratulations to CFSRE staff scientists: Barry K. Logan, PhD, F-ABFT, Amanda Mohr, MSFS, D-ABFT-FT, Alex J. Krotulski, MSFS & CFSRE Fellow: Donna Papsun, MS, FTS-ABFT
VIEW SOURCE:Wiley Drug Testing and Analysis
CFSRE Scientists Author Newly Published Article
Congrats to CFSRE Scientists:
- Melissa F. Fogarty, MSFS, D-ABFT-FT
- Alex J. Krotulski, MSFS
- Amanda L.A. Mohr, MSFS, D-ABFT-FT
- Barry K. Logan PhD, F-ABFT
..on the publication of their article: “The Detection of Novel Stimulants in Oral Fluid from Users Reporting Ecstasy, Molly and MDMA Ingestion”
During this 4-year study, 223 participants provided an oral fluid specimen and indicated recent use of Ecstasy, Molly and/or MDMA/MDA. For more information regarding the complete publication, please email: firstname.lastname@example.org.
Thomas Jefferson University PSM Forensic Science Open House!
TJU PSM Forensic Toxicology Open House
Saturday, November 17th 10:00AM-12:00PM
Are you interested in a career in Forensic Toxicology?
Jefferson University’s Professional Science Masters Degree in Forensic Toxicology will be hosting an Open House at The Center on Saturday, November 17th. Come meet our faculty and hear about “The Tox Files”, an eccentric set of presentations on interesting cases in forensic toxicology. Attendees will have a chance to tour our teaching facilities in addition to mingling with out staff scientists.
Interested students can register at http://explore.jefferson.edu/msforensictoxicologyinfosessionfall2018
TJU PSM Forensic Biology Open House
Saturday November 17th 1:00PM-3:00PM
Calling all Prospective Students!
Jefferson University’s Professional Science Masters Degree in Forensic Biology will be hosting an Open House at The Center on Saturday, November 17th. Prospective students will learn about “DNA and Foul Play: The Strange and Unexpected World of Forensic Biology”, in addition to mingling with our staff scientists and receiving a lab tour.
Interested students can register at http://explore.jefferson.edu/msforensicbiologyinformationsessionfall2018
Deaths from kratom, sold as an herbal supplement, are rising. But no one knows how much.
An unregulated herbal product that advocates say can relieve pain and help with opioid withdrawal has been linked to at least four deaths in the Philadelphia region, but with many authorities failing to track kratom poisonings, there’s no way to know if there are more deaths related to the substance. The CFSRE and NMS Labs’ own Dr. Barry Logan speaks out:
“NMS Labs, a nationally known forensic laboratory in Willow Grove, started testing for mitragynine about five years ago and is seeing more of it in postmortem toxicology cases, said vice president Barry Logan, a senior scientist. From January to June, there were 303 deaths in which mitragynine was found, often in combination with other opioids, he said.”
Check out this fascinating article posted on philly.com!VIEW SOURCE:Philly.com